ea0009p158 | Thyroid | BES2005
Giannios J
, Lambrinos P
, Michailakis E
, Maragudakis E
, Alexandropoulos N
Introduction:Anaplastic thyroid carcinoma has a very poor prognosis because it is a highly aggressive and extremely lethal human cancer with poor therapeutic responses due to intrinsic resistance to chemotherapy.One of the reasons is DNA methylation which causes silencing of tumour suppressor genes (TSGs).To improve the prognosis of patients with anaplastic thyroid Ca,a better understanding of the molecular changes involved in its pathogenesis is essential.<p class="abstex...